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Healthy People 2010 - with Annotations

Chapter 8

Injury and Violence Prevention
Lead Agency: Centers for Disease Control and Prevention

Infrastructure and Surveillance

8-24. Reduce exposure to pesticides as measured by blood and urine concentrations of metabolites.

Target and baseline:

Objective:
Reduction in Pesticide
Exposure as Measured by
Metabolites (Pesticide)
Blood/Urine Concentration
1988-94
Baseline*
2010
Target
8-24a.
1-naphthol (carbaryl)
36.0 micrograms/g creatinine 25.2 micrograms/g creatinine
8-24b.
Paranitrophenol
(methyl parathion and parathion)
3.8 micrograms/g creatinine 2.7 micrograms/g creatinine
8-24c.
3, 5, 6-trichloro-2-pyridinol
(chlorpyrifos)
8.3 micrograms/g creatinine 5.8 micrograms/g creatinine
8-24d.
Isopropoxyphenol
(propoxur)
1.6 micrograms/g creatinine 1.1 micrograms/g creatinine

*95 percent of the population had concentrations below this level.


Target setting method: 30 percent improvement.

Data source: National Health and Nutrition Examination Survey (NHANES), CDC, NCHS.

Note: Data are from a subset of NHANES data and are not nationally representative. Therefore, a population data template is not available.

Pesticides included in the table inhibit cholinesterase, an enzyme found in the human body. These pesticides are among those commonly used in the home and garden, agriculture, and industry.* Metabolites (or breakdown products) of pesticides are measured in urine samples obtained from persons aged 6 years and older. Urinary measurements of pesticide metabolites are an accurate way to measure recent exposure to pesticides that inhibit cholinesterase. Concentrations of pesticide metabolites in urine are corrected for kidney function and expressed in micrograms/g creatinine, a measure of kidney function.

*EPA. Pesticides Industry Sales and Usage; 1994 and 1995 Market estimates, 1997.


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Last modified: 10-Mar-2000.